Are you passionate about innovating at the intersection of biotech and new materials to
transform cancer diagnostics?
At Phos4nova, we are looking for a Preclinical Study Scientist who will lead the in vivo
validation of Phos4MR tracers. This role is central to demonstrating the clinical potential of our
technology in oncological models and later preparing the data packages required for clinical
trials.
Requirements:
● MSc, PhD or similar degree in Biomedical Science, Pharmacy, or a related field.
● Extensive expertise in cancer biology and in vivo tumor models, specifically GI cancers
tumors in the advanced metastatic disease stage.
● Knowledge about nanoparticle administration, biodistribution, targeting, and cell
uptake.
● Knowledge about the pharmaceutical development process, with an understanding of
regulatory requirements and clinical strategy planning.
● Experience with preclinical and clinical MRI scanners and imaging protocols is a plus.
Key Responsibilities:
● Design and execute and in vivo studies using wild type and disease animal models to
validate Phos4MR agents.
● Perform comprehensive data analysis, including pharmacokinetics, distribution
patterns, degradation profiles via MRI and NMR spectroscopy.
● Support formulation development and testing process.
● Carry out cellular uptake testing and histology.
● Collaborate with external Key Opinion Leaders (KOLs), CROs, and CDMOs to ensure
study designs align with GLP standards and clinical trial readiness.
Our offer:
We offer an exciting position in a dynamic startup where you will play a key role in the
development of innovative technology and grow as a biotech leader. The position is in
collaboration with Radboudumc and the main job location will be in Nijmegen. The position is
initially limited for 18 months (full or part-time) with a possibility to transition to a permanent
position in a leadership role as Phos4nova grows and reaches the next product development
stage. The earliest starting point is January 2027.
About Phos4nova:
Phos4nova B.V. is a deep-tech start-up and a spin-off of the University of Twente (UT)
incorporated in the beginning of 2024 in Enschede. As a purpose-driven startup that aims to
create clinical impact, Phos4nova innovates in the advanced materials, biotech, and
pharmaceutical sectors. The focus is on research and development of Phos4MR technology
advancing medical diagnostics and therapy monitoring.
To apply for a this job please send you CV and motivation letter to contact@phos4nova.eu
