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Senior Bioinformatician - Translational & Clinical Development UK (London) / Belgium (Brussels)
Senior Bioinformatician - Translational & Clinical Development UK (London) / Belgium (Brussels)
Job
Your Role
You will drive the integration and interpretation of omics, translational and clinical data from
patient studies to identify biomarkers, assess mechanisms of action, and inform clinical
decision-making.
Key Responsibilities
● Process, analyze, and interpret molecular datasets from clinical studies, including bulk
and single-cell transcriptomics, spatial transcriptomics, proteomics, and epigenomics.
● Develop robust, reproducible bioinformatics pipelines tailored to patient-level data
and regulatory standards.
● Apply methods for pathway and network analysis, functional enrichment, and causal
reasoning to derive clinical insights.
● Integrate omics and clinical variables to identify biomarkers of response, safety, or
stratification.
● Ensure traceability and compliance with data governance, privacy, and quality
standards in the clinical context.
● Prepare analytical reports, visualizations, and presentations for multidisciplinary
clinical and project teams as well as scientific publications.
● Contribute to internal documentation, study reports, and scientific publications.
Profile
Qualifications & Skills
Essential
● PhD or Master’s degree in Bioinformatics, Computational Biology, or related field, with
5–10 years of relevant experience in clinical or translational bioinformatics in a
business context.
● Strong expertise in analysis of patient-level omics data (bulk/single-cell RNA-seq,
proteomics, epigenomics, spatial data).
● Understanding of clinical study design, data privacy, and regulatory-compliant analysis.
● Proficiency in R and/or Python; experience with HPC, cloud, and containerization (e.g.,
Docker).
● Strong foundation in statistics, data mining, and visualization.
● Ability to work independently and deliver against deadlines, as well as to synergize
within interdisciplinary teams, enabling and empowering them to deliver high-quality
scientific results.Excellent written and verbal communication skills and the ability to
engage both scientific and clinical audiences. Excellent stakeholder management is
essential.
● Fluent in English.
Preferred
● Experience integrating omics with clinical and phenotypic data to inform biomarker
hypotheses.
● Familiarity with FAIR data principles, reproducible research, and GxP environments.
● Understanding of disease biology (neurology, immunology, rare disease) for contextual
interpretation.
● Track record of contributions to peer-reviewed publications or clinical project reports.
Benefits
What We Offer
● Opportunity to work in the UK (West-London) or Belgium (Brussels area)
● Opportunity to work embedded in our client’s clinical bioinformatics teams,
contributing directly to translational programs.
● Professional development through mentoring, training, and BioLizard’s global network
of experts.
● Collaborative, impact-driven culture where your analyses contribute to real patient
outcomes.
● Competitive compensation and benefits.
Company profile
Who are we?
BioLizard (“The Lizards”) is a leading bioinformatics consultancy that partners with biotech and
pharma organizations to bridge biology, data, and AI. Our mission is to unlock insights that
accelerate scientific innovation and clinical translation.
As a BioLizard consultant, you’ll work on-site in the UK -or in Belgium- and embedded as part
of the bioinformatics team of a pharma client, supporting Translational and Clinical
Development, contributing to different programs under development to bring novel therapies
to patients. You’ll apply your bioinformatics expertise to patient-level molecular data to
deepen understanding of treatment mechanisms, disease progression, and clinical response.
Contact
Interested? Get in touch!
Please send your CV with a one-page motivation to HR@lizard.bio
Find out more information at www.lizard.bio.
